Diagnostic Yield of Transbronchial Cryobiopsy in Diagnosis of Interstitial Lung Diseases

Laval University

Status: Unknown

Conditions: Interstitial Lung Disease

Treatments: Other: Transbronchial lung cryobiopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT02235779

CryobiopsieTBB

Details and patient eligibility

About

Evaluation of diagnostic yield, feasibility and safety of transbronchial lung cryobiopsies done via bronchoscopy in the investigation of interstitial lung disease in comparison with videothoracoscopy-assisted surgical lung biopsy.

Full description

See above

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Volunteer subjects with interstitial lung disease in whom a surgical lung biopsy is planned for diagnostic investigation.

Exclusion criteria

• Aged less than 18 y.o.
• Pregnancy
• Known coagulatoin disorder or blood dyscrasia
• Aaking antiplatelet agents other than aspirin or therapeutic anticoagulants drugs that cannot be safely discontinued to undergo lung biopsy
• Arterial oxgen pressure less than 60 mmHg on more than 2 liters per minute oxygen
• Known pulmonary hypertension defined as systolic PAP above 40 mmHg on echocardiography
• Unable to provide informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Cryobiopsy

Other group

Treatment:

Other: Transbronchial lung cryobiopsy