Diaphragm Ultrasound to Predict Posteroperative Residual Blockade

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Unknown

Conditions: Residual Curarization; Ultrasonography

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04321681

DiaphragmUltra

Details and patient eligibility

About

This study is a prospective observational research approved by the Ethics Committee of the Peking Union medical college Hospital. Patients scheduled for elective non-abdominal and non-thoracic surgery among age of 19-65 years and American Society of Anesthesiologists Physical Status Classification(ASA) I or II were inrolled. Diaphragm ultrasonogram was measured pre and post operation. Diaphragm excursion and diaphragm thickening fraction during quiet breathing as well as deep breathing were assessed. Neuromuscular monitor was performed during operation, after proper calibration.

Enrollment: 75 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Enrollment criteria：

1. Patients who were scheduled for elective non-abdominal and non-thoracic surgery in Peking Union medical college hospital.
2. age of 19-65 years
3. American Society of Anesthesiologists Physical Status Classification(ASA) I or II.
4. Agree to informed consent

Exclusion criteria ： Patients with neuromuscular diseases, diaphragmatic palsy, thoracic malformation, hand disabilities, chronic obstructive pulmonary disease, severe liver or kidney diseases, electrolyte or acid-base disorders, morbid obesity (body mass index ≥30 kg/m2), pregnancy, allergy to drugs used in the study, use of medication interfering neuromuscular transmission within 72hours and patients with predicted difficulty in maintenance of airway were excluded from this study. Written informed consent will be obtained before preoperative evaluation by an anesthesiologist.