Diaphragmatic and Pulmonary US for Extubation Success Prediction

Hospital Universitario Dr. Jose E. Gonzalez

Status: Completed

Conditions: Airway Extubation

Treatments: Device: Thoracic ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT02799056

NM16-00003

Details and patient eligibility

About

The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.

Full description

The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit. The investigators' null hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound can not predict the success of extubation in adult patients hospitalized in the intensive care unit.

The alternative hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.

The study is a no experimental study of diagnostic test, prospective with longitudinal capture. The study will consist of two parts: the first with the aim of finding the values best combination of sensitivity and specificity compared to extubation success for diaphragmatic shortening fraction and the number of lung quadrants with lines B. In the second part the study will make the prospective validation of these values.

Enrollment: 82 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of older
• Hospitalized in medical or surgical intensive care unit
• Successful spontaneous ventilation trial

Exclusion criteria

• Patients reintubated after a first failure after extubation
• Injuries to prevent conduct ultrasound
• Pregnancy
• History of neuromuscular disease
• Brain injury that prevented adequate protection of the airway (Glasgow Coma Scale <8)
• Unilateral or bilateral Pneumothorax
• Presence of chest tube in right hemothorax
• Right subphrenic abscess
• Known uni- or bilateral phrenic nerve injury
• Unilateral or bilateral diaphragmatic Paralysis
• Unwillingness of the patient or guardian to participate in the study