Diaphragmatic Thickness and Pulmonary Function in Parkinson's Disease

Abant Izzet Baysal University

Status: Completed

Conditions: Parkinson's Disease and Parkinsonism

Treatments: Other: No intervention, observational only

Study type: Observational

Funder types: Other

Identifiers

NCT05194748

AIBU-FTR-ETB-002

Details and patient eligibility

About

Ultrasound can give important information about the morphology of the diaphragm and the amount of contraction. Our aim, with the prediction that a restrictive pathology will occur in the pulmonary function with the addition of camptocormia in Parkinson's patients; to compare respiratory functions in Parkinson's patients with and without camptocormia, to investigate the correlation between ultrasonographically measured diaphragmatic thickness and pulmonary function test values.

Full description

Respiratory complications are one of the most common causes of death in Parkinson's patients. In Parkinson's disease, abnormal flexion of the thoracolumbar spine of 45° or more, which is called camptocormia, increases during walking or standing and disappears completely in the supine position. The prevalence of camptocormia among Parkinson's patients is about 7%. Camptocormia in Parkinson's disease is associated with significant disease disability, higher daily dopaminergic drug dosage, and cognitive impairment. Parkinson's patients with camptocormia often complain of shortness of breath, attributed to reduced pulmonary capacity due to limited chest expansion. Diaphragmatic dyskinesia in Parkinson's patients may also lead to a restrictive deterioration in respiratory functions.

Diaphragmatic thickness indicates diaphragmatic contraction and is correlated with PFT. Our aim; It is a comparison of respiratory functions in Parkinson's patients with and without camptocormia.

Enrollment: 37 patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being diagnosed with Parkinson's
• Volunteer to participate in the study

Exclusion criteria

• Being in contact with or suffering from COVID-19
• Having diseases that increase intra-abdominal pressure and venous insufficiency
• Having diseases that affect diaphragmatic motility
• Have had recent thoracic or abdominal surgery
• Having a parenchymal, pleural, or chest wall mass that may cause restriction on a recent chest X-ray or CT

Trial design

37 participants in 2 patient groups

camptocormia group

Description:

Diaphragmatic thickness will be measured by ultrasonography. Respiratory function will be evaluated by spirometric measurements. Postural deviations of the spine, knees, and hips will be recorded through photographs taken from the side and back

Treatment:

Other: No intervention, observational only

no camptocormia group

Description:

Diaphragmatic thickness will be measured by ultrasonography. Respiratory function will be evaluated by spirometric measurements. Postural deviations of the spine, knees, and hips will be recorded through photographs taken from the side and back

Treatment:

Other: No intervention, observational only