Diastolic Ventricular Interaction and the Effects of Biventricular Pacing in Hypertrophic Cardiomyopathy

University Hospitals Birmingham NHS Foundation Trust (UHB)

Status and phase: Unknown; Phase 3

Conditions: Hypertrophic Cardiomyopathy

Treatments: Device: Cardiac Resynchronisation Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00698074

05/Q2709/64

Details and patient eligibility

About

The primary aim of this study will be to assess whether Biventricular pacing improves exercise capacity, and Quality of Life in patients with symptomatic drug resistant Non-Obstructive Hypertrophic Cardiomyopathy, using a Biventricular pacemaker.

Enrollment: 32 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Symptomatic Hypertrophic Cardiomyopathy,

Exclusion criteria

• Rhythm other than normal sinus Left ventricular outflow tract gradient greater than 30mmHg Inability to exercise v02 max greater than 70% of predicted.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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32 participants in 1 patient group

1

Experimental group

Description:

Cardiac Resynchronisation Therapy

Treatment:

Device: Cardiac Resynchronisation Therapy