Diclofenac Potassium Alone Versus Diclofenac Potassium With Hyoscine-N-butyl Bromide (HBB in Endoscopy

Aljazeera Hospital

Status: Completed

Conditions: Pain

Treatments: Diagnostic Test: Diclofenac + HBB with hysteroscopy; Diagnostic Test: Diclofenav + placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT04125771

Diclofenac potassium

Details and patient eligibility

About

Diclofenac is a proven, commonly prescribed nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions.

Full description

Diclofenac is a proven, commonly prescribed nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions.

. As with all NSAIDs, diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1)

Enrollment: 64 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1. Patients indicated for diagnostic hysteroscopy including infertility, bleeding, suspected intrauterine pathologies (eg polypi , septea) 2. Reproductive age 20 - 40yrs

Exclusion criteria

• 1. Menopausal and amenorrhic patients 2. Contraindication to office hysteroscopy such as:- pelvic inflammatory disease, marked cervical stenosis, pregnancy

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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64 participants in 2 patient groups

Diclofenac + HBB

Other group

Description:

Women who will receive Diclofenac + HBB

Treatment:

Diagnostic Test: Diclofenac + HBB with hysteroscopy

Diagnostic Test: Diclofenav + placebo

Diclofenav + placebo

Other group

Description:

Women who will receive Diclofenav + placebo

Treatment:

Diagnostic Test: Diclofenac + HBB with hysteroscopy

Diagnostic Test: Diclofenav + placebo