Diet and the Aging Brain

University Hospital Muenster

Status and phase: Completed; Phase 3

Conditions: Healthy

Treatments: Behavioral: diet

Study type: Interventional

Funder types: Other

Identifiers

NCT00463255

Ernaehrung-Neuromod 01

Details and patient eligibility

About

We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.

Full description

The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as alzheimer's disease are a growing public-health concern with potentially devastating effects.

Refering to animal data and empirical studies, a healthy diet rich in unsaturated fatty acids and low in calories should improve cognitive functions such as learning and memory. To test this hypothesis, we study general brain functions in healthy elderly subjects (50-80 years old) during a short term diet.

Enrollment: 120 estimated patients

Sex: All

Ages: 50 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects
• 50-80 years old
• moderate to heavy weight
• must be able to change diet at home

Exclusion criteria

• diabetes
• younger than 50 years
• BMI < 23
• already participating in other studys
• MMSE > 26
• eating disorders

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)