ClinicalTrials.Veeva

Menu

Dietary Effects on Circulating Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Activity and Enzyme Activity in Peripheral Blood Mononuclear Cells (PBMCs) in Patients With Prediabetes or Newly Diagnosed Type 2 Diabetes

Yonsei University logo

Yonsei University

Status

Completed

Conditions

Impaired Fasting Glucose
Newly Diagnosed Type 2 Diabetes

Treatments

Dietary Supplement: Dietary intervention-whole grains and legumes
Dietary Supplement: Dietary intervention-Refined rice

Study type

Interventional

Funder types

Other

Identifiers

NCT01895387
FN20130614

Details and patient eligibility

About

We determined the effects of dietary intervention (replacement of refined rice with whole grains and legumes and a high intake of vegetables) on circulating Lp-PLA2 activity and enzyme activity in peripheral blood mononuclear cells (PBMCs) in patients with impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or newly-diagnosed type 2 diabetes.

Full description

Ninety-nine patients with impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or newly-diagnosed type 2 diabetes were randomly assigned to either a control group (usual diet with refined rice) or the whole grain group.

Enrollment

100 patients

Sex

All

Ages

39 to 74 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Subjects who were in in impaired fasting glucose (IFG, 100≤ fasting glucose <126 mg/dL)
  • or newly diagnosed type 2 diabetes (fasting glucose ≥126 mg/dL)

Exclusion criteria

  • current and/or past history of cardiovascular disease including angina
  • liver or kidney dysfunction
  • thyroid or pituitary disease
  • unstable weight loss/gain (≥2 kg) over the previous 12 months
  • pregnancy or lactation
  • taking medications or supplements

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

100 participants in 2 patient groups, including a placebo group

Whole grains and legumes
Experimental group
Treatment:
Dietary Supplement: Dietary intervention-whole grains and legumes
Refined rice
Placebo Comparator group
Treatment:
Dietary Supplement: Dietary intervention-Refined rice

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems