Dietary Effects on Weight Loss and Lipid Profile in Sedentary Men

P.L.Shupik National Medical Academy of Post-Graduate Education

Status: Completed

Conditions: Overweight; Lipid Metabolism Disorders; Life Style; Men; Obesity

Treatments: Dietary Supplement: LCD; Dietary Supplement: NCD

Study type: Interventional

Funder types: Other

Identifiers

NCT03082794

no Grant 4

Details and patient eligibility

About

Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of negative-calorie diet on weight loss and lipid profile, and to compare its efficiency with low-calorie diet in men.

Enrollment: 104 patients

Sex: Male

Ages: 45 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Non-smokers
• Weight-stable (± 2 kg, for more than one year)
• No history of regular exercise (in at least three months before the study).

Exclusion criteria

• History of medical disorders (CVD and other such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals, abnormality in thyroid or Electrocardiograph
• History of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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104 participants in 2 patient groups

Study group I

Experimental group

Description:

Study group I (53 participants) received the NCD (details of diet: 15% protein, 75% carbohydrates, 10% fat). Both groups had 15% caloric restriction from their maintenance energy requirements.

Treatment:

Dietary Supplement: NCD

Study group II

Experimental group

Description:

Study group II (51 participants) received the LCD or healthy weight maintenance diet (details of diet: 15% protein, 55% carbohydrates, 30% fat).Both groups had 15% caloric restriction from their maintenance energy requirements.

Treatment:

Dietary Supplement: LCD