Dietary Fibre and Chromium Picolinate Efficacy in Overweight and Obese Women (DFCP)

University of Roehampton

Status

Completed

Conditions

Overweight

Obesity

Treatments

Dietary Supplement: agglomerated glucomannan, oligofructose and chromium mixture

Study type

Interventional

Funder types

Other

Identifiers

NCT04250831

LSC 18/238

Details and patient eligibility

About

Obesity is one of the greatest causes of preventable morbidity and mortality worldwide with the main treatments requiring significant changes to lifestyle, particularly dieting and physical exercise. Glucomannan is a dietary fibre that expands in the stomach, creating the feeling of fulness, while chromium can regulate insulin response.

Full description

The aim of this pilot study was to investigate the effect of agglomerated glucomannan, oligofructose and chromium, as part of a calorie restricted diet plan, on weight loss, satiety, satiation, mood and gut microbiome composition in a human intervention study.

Enrollment

12 patients

Sex

Female

Ages

22 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

healthy female
aged 18-65 years
with a BMI between 25 and 35 kg/m2
not dieting within the previous four months
not having lost > 5% body weight in the previous year
not having increased physical activity levels in the past 2-4 weeks
intending to modify them during the study
able to eat most everyday foods

Exclusion criteria

BMI < 25 kg/m2
> 35 kg/m2
significant health problems
taking any medication or supplements known to affect appetite
weight within the past month and/or during the study
pregnant, planning to become pregnant or breastfeeding
history of anaphylaxis to food
known allergies or intolerance to foods and/or to the study materials or any of their stated ingredients.
Volunteers who were on specific food avoidance diets
with abnormal eating behaviour
receiving systemic or local treatment likely to interfere with the evaluation of the study parameters
smokers and those who have recently ceased smoking
Volunteers who work in appetite or feeding related areas volunteers who participated in another experimental study or receipt of