Dietary Monosaccharide Supplementation in Patients With Congenital Disorders of Glycosylation

Mayo Clinic

Status: Completed

Conditions: Congenital Disorder of Glycosylation

Study type: Observational

Funder types: Other

Identifiers

NCT04198987

18-007276

Details and patient eligibility

About

Researchers are trying to assess whether the use of simple sugars given as a daily dietary supplement can improve the health of children with congenital disorders of glycosylation (CDG).

Full description

The goal of this study is to collect data from patients diagnosed with congenital disorders of glycosylation and taking a simple sugar supplement. The study team wants to expand the evidence on the beneficial effects of this treatment in clinical practice.

Enrollment: 20 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient has a biochemically and genetically proven congenital disorder of glycosylation
• Patient is receiving (or planning to receive) oral simple sugar supplementation

Exclusion criteria

• Aldolase B deficiency
• Galactosemia
• Hemolytic uremic syndrome
• Severe anemia
• Galactose intolerance