Dietary Patterns, Inflammation, Zinc Status, and Body Composition in Multi-Ethnic Women of Reproductive Age in Jakarta (DIVERSE)

University of Indonesia (UI)

Status: Enrolling

Conditions: TNF Alpha; Zinc Status; Blood Pressure; Dietary Analysis; Body Composition

Treatments: Other: Not applicable- observational study

Study type: Observational

Funder types: Other

Identifiers

NCT07170904

NKB-298/UN2.RST/HKP.05.00/2024 (Other Grant/Funding Number)

DIVERSE (Protocol # KET-1848)

Details and patient eligibility

About

This study aims to determine the relationship between dietary patterns and hair zinc levels with body composition, tumor necrosis factor alpha (TNF-α), and blood pressure in women of reproductive age from different ethnic backgrounds in Jakarta, Indonesia (specifically Minangkabau, Sundanese, Javanese, Betawi, and Chinese). Participants are assessed once through dietary assessment, anthropometric measurements, and biological sample collection.

Full description

This cross-sectional observational study will evaluate dietary patterns and their association with nutritional status and inflammation in women of reproductive age. Participants will undergo dietary intake assessments (including the SQ-FFQ and a 3-day food diary), anthropometric and body composition measurements using the BOD POD (weight, height, fat mass, fat-free mass), and biospecimen sampling (blood and hair) for laboratory analysis of TNF-α and hair zinc concentrations. These findings are expected to offer information about dietary determinants and zinc micronutrient status that influence body composition, inflammation, and blood pressure in urban reproductive-age women from diverse ethnic backgrounds.

Enrollment: 188 estimated patients

Sex: Female

Ages: 19 to 49 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women aged 19-49 years
• Residing in Jakarta for at least 6 months
• Currently menstruating (not menopausal)
• From Minangkabau, Sundanese, Javanese, Betawi, or Chinese ethnicity
• Not pregnant or breastfeeding at the time of study

Exclusion criteria

• History of chronic diseases (e.g., diabetes, cardiovascular disease, cancer)
• Currently on a medically prescribed diet or taking medication affecting nutrient status
• Any condition interfering with accurate body composition measurement

Trial design

188 participants in 1 patient group

Women of Reproductive Age (WRA) Participants

Description:

A single group of women aged 19-49 years residing in Jakarta, Indonesia, from multi-ethnic backgrounds (Minangkabau, Sundanese, Javanese, Betawi, and Chinese). Participants undergo dietary assessment, body composition measurement using BOD POD, blood pressure measurement, and collection of hair and blood samples for zinc and TNF-α analysis.

Treatment:

Other: Not applicable- observational study