Dietary Phosphate and Serum Phosphorus

Linda W. Moore

Status

Completed

Conditions

Phosphorus Metabolism Disorders

Study type

Observational

Funder types

Other

Identifiers

NCT02435017

Pro00001798

Details and patient eligibility

About

Overall study design is to review National Health and Nutrition Examination Survey (NHANES) data 1999-2008 for nutrition risk according to kidney function. Substudies will be performed to review the association of nutrients and overall dietary intake compared to biomarkers available in NHANES during this period.

Full description

Data from NHANES 2003-2006 were used to evaluate the relationship between estimated dietary phosphorus intake and the measured serum phosphorus. The following variables were used:

Demographics: Age, sex, race/ethnicity Dietary variables: Foods, food groups (as reported by the United States Department of Agriculture (USDA) method, further standardized to the Academy of Nutrition and Dietetics method for portion size and then divided into groups having inorganic phosphate additives or no inorganic phosphate additives), food weight (g), phosphorus (mg), dietary supplements Socioeconomic variables: education, family income Laboratory variables: serum creatinine, phosphorus; urine albumin, creatinine Clinical assessments: hypertension (proportion having blood pressure ≥140 millimeters of mercury (mmHg) diastolic or ≥90 mmHg systolic or taking antihypertensive medications); hyperglycemia (proportion having serum glucose >126 mg/dL or taking medications for diabetes); kidney function based on Chronic Kidney Disease Epidemiology Collaboration (2009) equation, evaluated in 15 milliliters/min/1.73m2 increments from <15 to >105; anthropometrics (BMI, kg/m2; obesity class I, II, III)

Enrollment

7,895 patients

Sex

All

Ages

20 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria