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Dietary Vitamin A Requirement in Chinese Children and the New Technology of Dietary Assessment

H

Huazhong University of Science and Technology

Status

Completed

Conditions

Vitamin A Deficiency

Study type

Observational

Funder types

Other

Identifiers

NCT01559766
No.2008BAI58B03

Details and patient eligibility

About

Vitamin A deficiency remains a major public health problem in developing country worldwide. Young Children are considered to be at greatest risk of deficiency. However, there is little information on the vitamin A requirement of Chinese children. In the present study, about 400 children aged between 4 and 9 years old in a kindergarten and an elementary school of Shiyan City were screened before admission by questionnaire and anthropometric measurement. The vitamin A status of children was assessed by serum vitamin A level, relative dosage reaction and stable-isotope dilution technique. At the same time, their dietary vitamin A intakes were estimated by weighted-food dietary survey. The dietary vitamin A requirement in young children was determined on the basis of dietary vitamin A intakes in Children with adequate vitamin A level.

Enrollment

403 patients

Sex

All

Ages

4 to 9 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • well-nourished children with normal serum retinol(>=1.40umol/L)

Exclusion criteria

  • ongoing or previous illnesses,
  • having taken nutritional supplements within 3 months,
  • positive results in the fat absorption test or parasite test,
  • increased level of CRP (> 8 mg/L), or
  • lower serum level of retinol (< 1.40 umol/L)

Trial design

403 participants in 2 patient groups

4-6 years old group
7-9 years old group

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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