Difference Strain Ratio Ultrasound Elastography Between Benign and Malignant Peripheral Lung Lesions

Alexandria University

Status: Enrolling

Conditions: Peripheral Lung Lesions

Treatments: Radiation: CT chest; Procedure: Transthoracic biopsy

Study type: Observational

Funder types: Other

Identifiers

NCT05752227

0201692

Details and patient eligibility

About

Diagnostic accuracy study to investigate the sensitivity and specificity of sonographic elastography using strain ratio to differentiate between benign and malignant peripheral lesions in comparison to biopsy, clinically, or radiologically.

Full description

This is a diagnostic accuracy study with comparison to gold standard tests e.g., chest computed tomography, transthoracic biopsy, or microbiological analysis. All patients included in this study will give informed consent according to the guidelines of ethics committee, Alexandria Faculty of Medicine. (http://www.med.alexu.edu.eg/wp-content/uploads/2012/04/Checklist-FINAL- 20141.pdf-)

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1. Adult patients above age of 18 years old. 2) Patients with peripheral lung lesion.

Exclusion criteria

1. Pure pleural lesions.
2. Clinical instability to reach the final diagnosis.
3. Inaccessibility by ultrasound.

Trial design

120 participants in 2 patient groups

benign lung lesions

Description:

Patient who were diagnosed with peripheral lung lesions including consolidation, atelectasis, or cavitation

Treatment:

Procedure: Transthoracic biopsy

Radiation: CT chest

malignant lung lesions

Description:

patients diagnosed with malignant lung lesions

Treatment:

Procedure: Transthoracic biopsy

Radiation: CT chest