Differences in Exhaled Breath by Using Ion Mobility Spectrometry (IMS) in Subjects Tested for SARS-CoV-2 Infection (COVID-19 Disease)

B. Braun

Status: Completed

Conditions: SARS (Severe Acute Respiratory Syndrome); Covid19

Treatments: Device: Ion Mobility Spectrometry (IMS)

Study type: Observational

Funder types: Industry; Other

Identifiers

NCT04649931

HC-N-H-2006

Details and patient eligibility

About

Breath gas analysis is the evaluation of exhaled breath. It aims to evaluate the volatile organic compounds (VOCs) in exhaled breath.

In this feasibility study it is intended to find specific peaks/pattern in exhaled breath indicating an infection with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).

Enrollment: 450 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• PCR (= Polymerase Chain Reaction) testing for SARS CoV-2 will be/has been performed in a timely manner of sampling exhaled breath or PCR test for SARS-CoV-2 was performed within 96 hours, but preferably within 48 hours before sampling exhaled breath and PCR test result is already available
• Subject must be able to comply with study-specific procedures, e.g.is able to comply with breathing commands

Exclusion criteria

• Previous (history) SARS-CoV-2 infection, independent of the current episode
• Participation in a therapeutic study prior to breath analysis which could influence the result of the breath analysis