Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma

Technische Universität Dresden

Status: Completed

Conditions: High Tension Glaucoma; Normal Tension Glaucoma

Study type: Observational

Funder types: Other

Identifiers

NCT01488032

EK 322102010

Details and patient eligibility

About

The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.

Full description

It is till now not definitely clear whether normal- and high-tension glaucoma are different forms of the same disease and whether they have similar pathogenetic mechanisms. Spectral domain optical coherence tomography (SD-OCT) is supposed to objectively evaluate retinal nerve fiber layer (RNFL) thickness. The investigators propose a study to compare the RNFL in patients with normal- and high-tension-glaucoma. In order to exclude other possible differences,which could influence the results, only patients with similar structural optic nerve head damage in both groups will be compared.

Enrollment: 44 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• persons over 18 years
• men or women
• with normal- and high-tension glaucoma

Exclusion criteria

• cataract
• cloudy cornea and other conditions with bad visualisation quality of optic nerve head
• optic nerve atrophy except glaucomatous

Trial design

44 participants in 2 patient groups

high-tension glaucoma

Description:

subjects with IOP\>22 mmHg without eyedrops and signs of glaucomatous optic nerve damage

low-tension glaucoma

Description:

subjects with IOP\<22 mmHg without eyedrops and signs of glaucomatous optic nerve damage