Differences in Ovarian Aging Between Caucasian and Indian Women

IVI Madrid

Status: Completed

Conditions: Age of the Patients and the Body Mass Index in Both Groups

Study type: Observational

Funder types: Other

Identifiers

NCT02210013

MAD-CI-01-2012-01

Details and patient eligibility

About

The investigators want to carry out a prospective study of 400 infertile Caucasian and Indian women who will undergo a controlled ovarian stimulation for in vitro fertilization (IVF). The investigators will collect data about ovarian reserve markers and also the results after ovarian stimulation in both ethnic groups.The aim is to identify differences in ovarian response after IVF stimulation between both groups.

Full description

A total of 200 Caucasian patients and 200 Indian patients who will attend the first or second IVF cycle will be included.

The date we will collect in both groups include the age, the body mass index, and the ovarian reserve markers like the antral follicle count (AFC), the follicle stimulation hormone (FSH) and antimullerian hormone (AMH) serum levels.

The investigators will also determine the number of oocytes retrieved and the metaphase two oocytes in both groups after IVF stimulation.

Enrollment: 400 patients

Sex: Female

Ages: 18 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women aged < 42 years old, with both ovaries present, undergoing a first or second IVF treatment due to male factor, tubal disease or previous failed intrauterine insemination (IUI).

Exclusion criteria

• Women diagnosed of polycystic ovary syndrome according to Rotterdam criteria, endometriosis stage III-IV, or previous pelvic inflammatory disease.

Trial design

400 participants in 2 patient groups

Caucasian women

Description:

200 Caucasian infertile women undergoing their first or second IVF cycle

Indian women

Description:

200 Indian women undergoing their first or second IVF cycle.