Different Chemotherapy Protocols Combined With Intensity Modulated Radiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

Luo yanrong

Status: Completed

Conditions: Drug-Related Side Effects and Adverse Reactions

Treatments: Drug: Cisplatin; Drug: Docetaxel

Study type: Interventional

Funder types: Other

Identifiers

NCT03177174

S2017-030-02

Details and patient eligibility

About

This study was to evaluate the efficacy ,toxic reaction and safety of different chemotherapy combined with radiotherapy on patients with locally advanced nasopharyngeal carcinoma.

Enrollment: 150 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients > 18, <70 years old, with locally advanced nasopharyngeal carcinoma.

Exclusion criteria

• patients who had accepted radiotherapy before patients with any ather types of cancer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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150 participants in 3 patient groups

Docetaxel

Active Comparator group

Treatment:

Drug: Docetaxel

Cisplatin

Active Comparator group

Treatment:

Drug: Cisplatin

DocetaxelCisplatin

Active Comparator group

Description:

Cisplatin combined with Docetaxel

Treatment:

Drug: Cisplatin

Drug: Docetaxel