Different Crystalloids on AKI in Shock

Southeast University, China

Status: Unknown

Conditions: Shock

Treatments: Other: Fluid resuscitation

Study type: Observational

Funder types: Other

Identifiers

NCT03155126

2017ZDSYLL017P01

Details and patient eligibility

About

The goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Full description

Fluid resuscitation is important to shock patients. Saline is the classical fluids for resuscitation. However, studies showed that resuscitation with saline could increase the incidence of hyperchloremia and acute kidney injury. Thus, the goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Enrollment: 600 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Shock patients who need fluid resuscitation with risk factors of acute kidney injury

Exclusion criteria

• Patients with a history of chronic kidney injury and hemodialysis therapy

Trial design

600 participants in 2 patient groups

Saline group

Description:

Patients resuscitated with saline

Treatment:

Other: Fluid resuscitation

Acetated Ringer's sodium group

Description:

Patients resuscitated with Acetated Ringer's sodium

Treatment:

Other: Fluid resuscitation