Different Endoscopic Gastric Cancer Risk Assessments

Yanqing Li

Status

Enrolling

Conditions

Gastric Cancer Screening

Treatments

Procedure: Kimura-Takemoto classification

Procedure: EGGIM

Study type

Interventional

Funder types

Other

Identifiers

NCT05458388

2022-SDU-QILU-120

Details and patient eligibility

About

The Kimura-Takamoto classification established in Japan can observe the extent of gastric atrophy in real-time under endoscopy, and diffuse atrophy also indicates an increased risk of gastric cancer. Recent studies have found that the evaluation of intestinal metaplasia score (EGGIM score) of various stomach parts by electronic staining can well identify OLGIM III\ IV patients. Although the Kimura-Takamoto classification and EGGIM score can evaluate the risk of gastric cancer in patients, only in cross-sectional studies, it is not clear the diagnostic value of risk assessment in population screening. Early gastric cancer has the characteristics of hidden lesions and a high rate of clinical missed diagnosis. Concentrating high-risk groups through risk scores is expected to guide endoscopic doctors to conduct a targeted careful examination. However, it is not clear whether Kimura-Takamoto classification and EGGIM score can improve the detection rate of early gastric cancer in clinical practice.

Enrollment

3,500 estimated patients

Sex

All

Ages

40 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients aged 40-80 years undergoing gastroscopy
Patients intend to undergo ESD treatment

Exclusion criteria

patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric disorders who cannot participate in gastroscopy
Patients with previous surgical procedures on the stomach
patients with contraindications to biopsy
Patients who refuse to sign the informed consent form.