Different Intravitreal Injection Techniques and Pain Level

Clalit Health Services

Status: Unknown

Conditions: Injection Site Discomfort

Treatments: Other: Technique of injection

Study type: Interventional

Funder types: Other

Identifiers

NCT02497092

0021-15-RMC

Details and patient eligibility

About

The purpose of this study is to determine whether certain intravitreal injection techniques cause less pain than others and would therefore be beneficial for the patient's well being.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients receiving intravitreal anti vascular endothelial growth factor (VEGF) injections
• Informed consent

Exclusion criteria

• Dementia or any other reason for cognitive deterioration
• Technical limitations not allowing injecting by the protocol

Trial design

300 participants in 4 patient groups

Slow angled injection

Active Comparator group

Description:

Slow and angled insertion of the needle through the sclera

Treatment:

Other: Technique of injection

Slow straight injection

Active Comparator group

Description:

Slow and straight insertion of the needle through the sclera

Treatment:

Other: Technique of injection

Fast angled injection

Active Comparator group

Description:

fast and angled insertion of the needle through the sclera

Treatment:

Other: Technique of injection

Fast straight injection

Active Comparator group

Description:

fast and straight insertion of the needle through the sclera

Treatment:

Other: Technique of injection