Different Risk Stratification Models for Prediction of Lymph Node Involvement in Endometrial Carcinoma

Assiut University

Status: Completed

Conditions: Endometrial Cancer

Treatments: Procedure: hysterectomy

Study type: Observational

Funder types: Other

Identifiers

NCT04120649

RSMLI

Details and patient eligibility

About

Endometrial cancer is the most common malignant disease of the female genital tract and the seventh most common cause of cancer death in women in Western countries. Histological type, grade and depth of myometrial invasion are prognostic factors in early stage disease as well as risk factors for lymph node metastasis. Systematic lymphadenectomy has recently been questioned for stage I disease based on the results from two randomized trials

Enrollment: 50 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Not virgin
• Not having congenital anomalies
• Early stage
• Body mass index less than 35

Exclusion criteria

• virgin
• advanced stage
• sever infection especially in the pelvis
• lymphadenopathy for any cause
• lymphadenectomy for any cause
• BMI more than 35
• Synchronous malignancies

Trial design

50 participants in 1 patient group

endomterial cancer

Description:

All patients visiting the clinic at Women Health Hospital who having endometrial carcinoma with their diagnosis based on investigations (tumor marker ) , imaging, histopathology will have surgical staging consisted of total hysterectomy, bilateral salpingo-oopherectomy (based on the age of the patient), pelvic and para-aortic lymphadenectomy, and peritoneal washings

Treatment:

Procedure: hysterectomy