Different Surgical Approaches for Treatment of UPJ Obstruction in Children: Prospective Randomized Clinical Trial

Assiut University

Status: Not yet enrolling

Conditions: Surgery; Urologic Diseases

Treatments: Procedure: Laparoscopic pyeloplasty

Study type: Observational

Funder types: Other

Identifiers

NCT05748964

AKA1712

Details and patient eligibility

About

This study aimed to evaluate the clinical efficacy of laparoscopic pyeloplasty (LP) for ureteropelvic junction obstruction (UPJO) via retroperitoneal and transperitoneal approaches.

Full description

Ureteropelvic junction obstruction (UPJO) is the most common congenital abnormality of the kidney and is responsible for flank pain, recurrent urinary infections, hydronephrosis and the loss of renal function. Until recently, open pyeloplasty (OP) was the standard surgical treatment modality for UPJO.However, with the development of laparoscopic devices and surgical technology, laparoscopic pyeloplasty (LP) has become a more beneficial choice for the patients with UPJO than open surgery because of the advantages of excellent visualization, minimal trauma, rapid postoperative recovery, good cosmetic result, and a nearly successful rate compared with open pyeloplasty. The first LP in children was performed in 1995. It has gained popularity for older children. LP can be performed though retroperitoneal and transperitoneal approaches. Which surgical method is better is still controversial.

Enrollment: 20 estimated patients

Sex: All

Ages: 2 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age above two years.
• Unilateral UPJO.

Exclusion criteria

• Age below two years.
• Bilateral UPJO.
• Recurrent UPJO.
• Malrotated kidneys and renal fusion anomalies.

Trial design

20 participants in 2 patient groups

Transperitoneal approach laparoscopic pyeloplasty. (TALP)

Description:

Transperitoneal approach laparoscopic pyeloplasty. (TALP)

Treatment:

Procedure: Laparoscopic pyeloplasty

Retroperitoneal Approach laparoscopic pyeloplasty. (RALP)

Description:

Retroperitoneal Approach laparoscopic pyeloplasty. (RALP)

Treatment:

Procedure: Laparoscopic pyeloplasty