Different Treatment Modalities for Oral Lichen Plan

Al-Azhar University

Status and phase: Completed; Phase 1

Conditions: Oral Lichen Planus

Treatments: Device: 980 nm diode laser; Drug: 0.1% topical triamcinolone Acetonide preparation "Kenacourt-A Orabase"

Study type: Interventional

Funder types: Other

Identifiers

NCT06681090

Management of Oral Lichen Plan

Details and patient eligibility

About

The goal of applications of Low-Level Laser and Topical Steroid in the Management of Oral Lichen Planus is to learn if intervention can by relieve pain, decreasing inflammation, and facilitating tissue healing in20 patients who were suffering from erosive oral lichen planus. The main questions it aims to answer are which is better and more effective as treatment modality. The erosion size (mm2) measured on the first day and 4 weeks later. Oral Health-Related Quality of Life questionnaire manipulated. Researchers will take Low-Level Laser and Topical Steroid in the Management of Oral Lichen Planus to see if it could be used as separate treatment option or as combination.

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who were monitored for OLP.
• clinical and histopathological finding of OLP in accordance with van der Meij 2003.
• being over 18 years old.

Exclusion criteria

• Patients with systemic disorders, pregnancy, using drugs, smoking, lesions in contact with dental amalgams, and cutaneous or other mucosal involvement at the time of treatment were excluded.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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20 participants in 2 patient groups

Topical Steroid Therapy of Erosive oral lichen planus

Experimental group

Description:

topical application of 0.1% triamcinolone acetonide and photo biomodulation on erosive oral lichen planus, 3 times daily and a miconazole oral gel once daily, for 4 weeks

Treatment:

Drug: 0.1% topical triamcinolone Acetonide preparation "Kenacourt-A Orabase"

Low-Level Laser Therapy of Erosive oral lichen planus

Experimental group

Description:

Photo biomodulation with laser therapy twice a week for 8 sessions over 4 weeks, utilizing a 980 nm diode laser with an output power of 300 mw.

Treatment:

Device: 980 nm diode laser