ClinicalTrials.Veeva

Menu

Differential Diagnosis and Risk Stratification in Patients With Suspected NSTEACS

N

National Research Center for Preventive Medicine

Status

Completed

Conditions

Non ST Segment Elevation Acute Coronary Syndrome

Treatments

Diagnostic Test: Approaches to differential diagnosis and risk stratification

Study type

Observational

Funder types

Other

Identifiers

NCT04400500
01-02/20

Details and patient eligibility

About

To evaluate possibilities of rapid differential diagnosis and risk stratification in patients urgently admitted to the CCU with a suspected acute coronary syndrome without persistent ST-segment elevation (NSTEACS).

Full description

Single centre prospective non-randomised non-comparative study of patients delivered by ambulance and admitted to the CCU with suspected NSTEACS.

Aims of this study are:

  1. To characterize the contingent of patients admitted to the CCU with suspected NSTEACS.
  2. To evaluate possibilities of fast differential diagnosis and risk stratification in patients admitted to the CCU with suspected NSTEACS using clinical data, ECG, biomarker levels (hsTn, NT-proBNP, hsCPR, cardiac FABP) as well as HEART, ADAPT, EDACS, T-MACS, GRACE, ACTION and TIMI scores.
  3. To evaluate the correlation between clinical data, ECG, biomarker levels (hsTn, NT-proBNP, hsCPR, cardiac FABP) as well as HEART, ADAPT, EDACS, T-MACS, GRACE, ACTION and TIMI scores with presence and severity of coronary atherosclerosis in patients admitted to the CCU (intensive care unit) with suspected NSTEACS.

Enrollment

140 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Delivered by ambulance to the CCU with suspected diagnosis "acute coronary syndrome (ACS)".
  2. Signed informed consent.

Exclusion criteria

  1. ACS with persistent ST-segment elevation.
  2. Moribund; extremely severe condition on admission with a potentially unfavourable prognosis (cardiogenic shock, coma, cardiac arrest, an urgent need for mechanical ventilation).
  3. Overt non-cardiac cause of clinical manifestations at the time of admission (bleeding, pulmonary embolism, aortic dissection, stroke).

Trial design

140 participants in 1 patient group

Suspected NSTEACS
Description:
Patients urgently admitted to the CCU with suspected NSTEACS
Treatment:
Diagnostic Test: Approaches to differential diagnosis and risk stratification

Trial contacts and locations

1

Loading...

Central trial contact

Igor S Yavelov, PhD; Vitaliy A Moshanov, RA

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems