Differential Effects of a Diet Supplementation With Plant Sterol Esters on Human Monocytes (PSE-MO)

University Hospital, Saarland

Status: Unknown

Conditions: Hyperlipidemia

Treatments: Dietary Supplement: margarine (placebo); Dietary Supplement: margarine + plant sterol esters

Study type: Interventional

Funder types: Other

Identifiers

NCT00928616

108/07

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of a diet supplementation with plant sterol esters on serum lipids, plant sterol concentrations and monocyte subpopulations.

Full description

This study investigates effects of a diet supplementation with plant sterol esters on serum lipids, plant sterol concentrations and monocyte subpopulations.

Enrollment: 16 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy individuals without known cardiovascular diseases

Exclusion criteria

• drugs that interfere with cholesterol metabolism
• other use of dietary supplements
• vegetarianism

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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16 participants in 2 patient groups, including a placebo group

plant sterol esters

Experimental group

Description:

Participants consume plant sterol ester supplemented margarine (3 g/day)

Treatment:

Dietary Supplement: margarine + plant sterol esters

Placebo

Placebo Comparator group

Description:

Placebo is a non-sterol ester supplemented margarine

Treatment:

Dietary Supplement: margarine (placebo)