Differential Expression and Analysis of Peripheral Plasma Exosome miRNA in Patients With Myocardial Infarction

Shanghai Jiao Tong University

Status: Unknown

Conditions: Myocardial Infarction

Treatments: Other: exosome

Study type: Observational

Funder types: Other

Identifiers

NCT04127591

XH-19-010

Details and patient eligibility

About

The aim of this study is to determine the miRNA expression profile in peripheral blood exosomes of patients with myocardial infarction and to investigate its relationship with myocardial infarction.

Full description

Collect exosomes in peripheral blood of patients with myocardial infarction, compare the expression of miRNA with healthy volunteers, find out the miRNAs with significant differences, and explore its relationship with the development of myocardial infarction.

Enrollment: 10 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age > 18 years ST elevation by ECG diagnostic of STEMI Evidency of coronary occlusion in coronariography Signed informed consent

Exclusion criteria

• Patients who will undergo immediate PCI Pregnant and lactating women Patients with mental disorders Patients are using other experimental drugs; Refusal to provide informed.

Trial design

10 participants in 2 patient groups

myocardial infarction group

Description:

Patients admitted with the diagnosis of myocardial infarction.

Treatment:

Other: exosome

Blank control group

Description:

Patients admitted without the diagnosis of myocardial infarction.

Treatment:

Other: exosome