Differing Levels of Positive Anti-Neutrophil Cytoplasm Antibody (ANCA) Test and Their Correlation With Vasculitis or Malignancy or Chronic Inflammation

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Treatments: Other: Follow-up

Study type: Observational

Funder types: Other

Identifiers

NCT02180126

HYMC0041-14

Details and patient eligibility

About

A positive Anti-Neutrophil Cytoplasm Antibody (ANCA) test administered to patients with a high probability for vasculitis has high sensitivity and specificity for vasculitis. A positive ANCA test result in those patients who do not have a high probability for vasculitis requires extensive follow-up because those patients eventually present with malignancy or other inflammatory diseases. The investigators wish to investigate the correlation between the differing levels of positive ANCA tests and their relationship to vasculitis, malignancy and inflammatory diseases.

Enrollment: 160 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with borderline positive ANCA test results

Exclusion criteria

• Pregnant

Trial design

160 participants in 1 patient group

Positive ANCA

Description:

Patients with borderline positive ANCA results.

Treatment:

Other: Follow-up