Diffusion -and Perfusion Weighted MRI for Response Prediction of Symptomatic Leiomyomas Following Uterine Artery Embolization

Universitaire Ziekenhuizen KU Leuven

Status: Active, not recruiting

Conditions: Leiomyomas

Treatments: Procedure: Diffusion -and perfusion weighted MRI including iv contrast agent injection

Study type: Interventional

Funder types: Other

Identifiers

NCT01514617

S53666

Details and patient eligibility

About

It is known that volumetric response of leiomyomas following uterine artery embolization correlates well with patients clinical outcome. The aim of this study is to assess diffusion -and perfusion weighted MRI for the prediction of volumetric response following uterine artery embolization in patients with symptomatic leiomyomas.

Enrollment: 100 estimated patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• women with symptomatic leiomyomas

Exclusion criteria

• women with known contra-indications for MRI (cardiac pacemaker, cochlear implants, claustrophobic patients)
• women with contra-indications to gadolinium-based contrast agents (including patients with a known restricted renal function; GFR < 30 mL/min)

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind