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Diffusion Tensor (DTI) for the Assessement of Therapeutic Evolution of Patients With Acute Lumbar Radiculalgia (DiTi-Aïe)

L

Lille Catholic University

Status

Enrolling

Conditions

Diffusion Tensor Imaging
Lumbar Radiculopathy
Magnetic Resonance Imaging

Treatments

Other: DTI sequence acquisition

Study type

Interventional

Funder types

Other

Identifiers

NCT04507113
RC-P0074

Details and patient eligibility

About

Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots. DTI is a widely used neuroimaging technique and is a current topic of research in the field of peripheral nerve imaging.The aim of the study is to determine the prognostic quality of the DTI parameters to predict the therapeutic evolution of patients with lumbar radiculalgia at 6 months.

Enrollment

150 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age ≥ 18 ans
  • Patient with Lumbar Radiculalgia (L4, L5 or S1)
  • Pain VAS (Visual analog scale) > 30/100
  • Less than 3 months of evolution
  • With a radiculalgia superior or equal to lumbalgia
  • Disco radicular conflict, verified by MRI
  • Able to receive information
  • Affiliated to French social security

Exclusion criteria

  • History of chronic lumbalgia and radiculalgia
  • History of lumbar surgery
  • Recent episode (less than 6 months) with the same radicular topography
  • Bilateral radicular compression on MRI
  • Patient requiring emergency surgery
  • Evolutive disease interfering with pain assesment (neoplasia, inflammatory rheumatism, peripheral neuropathy, central neurological disease)
  • MRI contraindication

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

150 participants in 1 patient group

Lumbar radiculopathy
Experimental group
Description:
Patients with acute lumbar radiculopathy (less than 3 months of evolution)
Treatment:
Other: DTI sequence acquisition

Trial contacts and locations

1

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Central trial contact

Lucile POISSON, PhD; Marie Paule LEBITASY, MD, PhD

Data sourced from clinicaltrials.gov

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