Diffusion-tensor Imaging in Brain Tumors Evaluation

George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures (UMFST)

Status: Unknown

Conditions: MRI; Diffusion Tensor Imaging; Tractography

Treatments: Diagnostic Test: MRI

Study type: Observational

Funder types: Other

Identifiers

NCT05261724

GEPaladeU

Details and patient eligibility

About

Primary and secondary brain tumors are challenging pathologies regarding diagnosis and treatment. MRI is widely used in the imaging evaluation and surgical planning, due to its spatial resolution and ability of tissular characterization.

In this study patients with suspected brain tumors, confirmed by routine MRI evaluation (T1, T2, T2*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation. By analyzing collected data from MRI evaluation and patient records regarding surgical and histopathological data our aim is to investigate derived imaging biomarkers with impact in the surgical planning and rehabilitation of the patients.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• brain tumors confirmed by routine MRI evaluation
• surgical treatment with histopathological diagnosis

Exclusion criteria

• MRI contraindications
• past or present neurological or neurosurgical condition, beside the tumor
• pregnancy

Trial design

100 participants in 2 patient groups

Patients with primary brain tumors

Treatment:

Diagnostic Test: MRI

Patients with secondary brain tumors

Treatment:

Diagnostic Test: MRI