Diffusion Tensor Sequences (DTI) for Study of Lumbar Roots by Magnetic Resonance Imaging (MRI) (OPTI-DTI)

Lille Catholic University

Status: Completed

Conditions: MRI; Diffusion Tensor Imaging; Radiculopathy Lumbar

Treatments: Diagnostic Test: Optimisation of DTI sequences

Study type: Interventional

Funder types: Other

Identifiers

NCT04224077

RC-P0060

Details and patient eligibility

About

Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots. DTI is a widely used neuroimaging technique and is a current topic of research in the field of peripheral nerve imaging. The aim of this work is therefore to improve DTI sequences by specifically evaluating the contribution of the multiband technique in healthy volunteers.

Full description

For every healthy volunteer will be acquired:

• a morphological sequence
• a reference diffusion tensor sequence covering three lumbar stages (reference DTI),
• a diffusion tensor sequence acquired in multiband technique, covering three lumbar stages (optimized DTI),
• a diffusion tensor sequence acquired in a multiband technique, covering a lumbar stage, of higher spatial resolution (centred DTI)

Enrollment: 20 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Person without history of lumbar surgery
• Person who has previously consented

Exclusion criteria

• MRI contraindications (pace maker, cardiac defibrillator,...)
• Claustrophobia
• Pregnant woman
• Person without social security
• Person with a guardianship
• Person carrying metallic surgical material (spine, pelvis, abdomen)

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Intervention

Experimental group

Description:

Healthy volunteers

Treatment:

Diagnostic Test: Optimisation of DTI sequences