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Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.

M

Medical University of Bialystok

Status

Unknown

Conditions

Ischemic Optic Neuropathy
Hereditary Optic Neuropathies
Compressive Optic Neuropathy
Toxic Optic Neuropathy
Traumatic Optic Neuropathy
Optic Neuritis

Treatments

Diagnostic Test: VEP - visual evoked potential
Diagnostic Test: Ophthalmology examination.
Device: Neuroimaging

Study type

Interventional

Funder types

Other

Identifiers

NCT05353413
R-I-002/477/2019

Details and patient eligibility

About

The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging

Full description

In this study, it is planned to find twenty volunteers for each of the neuropathies and twenty healthy volunteers. Each volunteer will undergo clinical tests such as visual acuity, color vision, intraocular pressure measurement, assessment of the anterior chamber and fundus using a slit lamp and Volk lens, macular optical coherence tomography examination and examination of the optic nerve disc (OCT), neurological field vision and visual evoked potential (VEP) testing. Each of the volunteers will undergo magnetic resonance imaging. During active scanning, patients will be asked for not blinking or moving their heads by staring at the red dot on the outside of the camera reflected in the coil mirror. The obtained diffusion tensor data will be used for further analysis.

Enrollment

20 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Optic neuropathy.

Exclusion criteria

common contraindications to MRI (presence of pacemaker, non-MRI-safety or claustrophobia)

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

20 participants in 2 patient groups

Various types of optic neuropathies
Experimental group
Description:
Patients with various types of optic neuropathy.
Treatment:
Device: Neuroimaging
Diagnostic Test: Ophthalmology examination.
Diagnostic Test: VEP - visual evoked potential
Healthy volunteers
Other group
Description:
Healthy volunteers
Treatment:
Device: Neuroimaging
Diagnostic Test: Ophthalmology examination.
Diagnostic Test: VEP - visual evoked potential

Trial contacts and locations

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Data sourced from clinicaltrials.gov

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