Diluting With Cerebrospinal Fluid Versus Traditional Intrathecal Administration: Antishivering Effects

China Medical University, China

Status: Withdrawn

Conditions: Antishivering Effects

Treatments: Procedure: bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid

Study type: Interventional

Funder types: Other

Identifiers

NCT02189655

20140630

Details and patient eligibility

About

This prospective randomized double-blinded study was conducted to compare the antishivering effects of two different types of intrathecal administration.

Full description

This prospective randomized double-blinded study was conducted to compare the antishivering effects of two different types of intrathecal administration.Group Control:traditional intrathecal administration; Group Diluting:Diluting with cerebrospinal fluid

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA) physical status Ⅰ or Ⅱ who were scheduled for elective surgery under spinal anesthesia were enrolled.

Exclusion criteria

• Patients with pre-operative fever (>38℃), diabetes, , Parkinson's disease, hypo or hyperthyroidism, Raynaud's syndrome, obese patients (weight >100 kg), patients shorter than 152 cm, those with a history of allergy to the study medications, and patients receiving vasodilators were excluded from the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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0 participants in 2 patient groups

Group Control

No Intervention group

Description:

Hyperbaric bupivacaine 0.5% 2.5 mL was administered intrathecally in 30 seconds.

Group Diluting with cerebrospinal fluid

Experimental group

Description:

Hyperbaric bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid was administered intrathecally in 30 seconds

Treatment:

Procedure: bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid