Diode Laser-Assisted Periodontal Therapy Enhances Clinical Outcomes for Deep Periodontal Pockets in Smokers

Selcuk University

Status

Completed

Conditions

Periodontitis Stage III

Periodontitis

Malondialdehyde

Diode Laser Therapy

Smoking

Periodontal Disease

Treatments

Procedure: Professional Mechanical Plaque Removal

Device: Diode Laser Application in Deep Periodontal Pockets

Procedure: Scaling and Root Planing

Study type

Interventional

Funder types

Other

Identifiers

NCT07213752

SU-DIAE-01

Details and patient eligibility

About

This study investigated the adjunctive effects of diode laser therapy in smokers with severe periodontitis. Thirty-three patients were randomized to non-surgical periodontal therapy (SRP) with or without diode laser. Clinical parameters and salivary oxidative stress markers (MDA, 8-OHdG) were assessed at baseline, 1, and 3 months. Both groups showed improvements, but SRP+DL resulted in significantly greater reductions in deep pockets, PISA, PESA, PI, and MDA at 3 months. These findings suggest that diode laser therapy may enhance conventional treatment by improving clinical outcomes and reducing oxidative stress in smokers with severe periodontitis.

Enrollment

33 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

no periodontal treatment within the previous 6 months;
no use of antibiotics within the previous 3 months;
no systemic disease and alcohol drinkers, or drug users;
no use of anti-inflammatory drugs within the past 3 months;
no pregnancy;
no use of hormonal contraceptives; and
current smokers with a history of smoking ≥10 cigarettes per day for at least one year.

Exclusion criteria

Patients with <20 teeth, grade III tooth mobility, partial dentures, or fixed prostheses were excluded. Additionally, those with dental implants or peri-implant diseases were also excluded.