Diosmin as Adjuvant Therapy in Treatment of Non-bleeding Peptic Ulcer

Tanta University

Status and phase: Enrolling; Phase 3

Conditions: Non-bleeding Peptic Ulcer

Treatments: Drug: Diosmin

Study type: Interventional

Funder types: Other

Identifiers

NCT05670457

diosmin peptic ulcer

Details and patient eligibility

About

The aim of the study is to evaluate the safety and efficacy of diosmin as adjuvant therapy in treatment of non-bleeding peptic ulcer patients.

Enrollment: 44 estimated patients

Sex: All

Ages: 25 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

-. Age 25-65 years old.

• Patients of both gender (male and female).
• Non-bleeding Peptic ulcer Patients (duodenal &gastric) diagnosed by endoscopy.

Exclusion criteria

• The presence of other factors that can lead to gastric bleeding other than peptic ulcer.

  • Patients with cancerous disease
  • Breast-feeding.
  • Surgically altered stomach ( bariatric surgery),
  • Patient with liver disease.

• Bleeding & perforated peptic ulcer.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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44 participants in 2 patient groups

Control group

No Intervention group

Description:

this group will include 22 patients who will receive anti peptic ulcer only for 2 months.

Diosmin group

Active Comparator group

Description:

this group will include 22 patients who will receive anti peptic ulcer and diosmin 500 mg twice daily for 2 months.

Treatment:

Drug: Diosmin