Direct Versus US Guided PECS Block on Controlling Postmastectomy Pain

Al-Azhar University

Status: Completed

Conditions: Postmastectomy Pain

Treatments: Procedure: Ultrasound guided pecs block; Procedure: Direct pecs block; Drug: general anaesthetic technique only

Study type: Interventional

Funder types: Other

Identifiers

NCT05825430

RC.5.1.2023

Details and patient eligibility

About

Perioperative analgesia for surgery in carcinoma breast utilizes significant quantities of opioids as compared to cosmetic breast surgeries. Regional anesthesia reduces the need for perioperative opioids and thus may improve the outcome. The investigators decided to perform the modified pectoral nerve block ( Pec II) under vision after resection of tumor, without ultrasound and compare the postoperative analgesic and opioid sparing effects of the nerve block with ultrasound guided modified pectoral nerve block (Pec) in patients undergoing modified radical mastectomy.

Enrollment: 60 patients

Sex: Female

Ages: 20 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 20 - 50 years
• ASA I or II undergo elective simple mastectomy

Exclusion criteria

• patients with diabetes mellitus i
• Intradialytic hypotension,
• chronic kidney disease and Bronchial Asthma

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

Control group

Experimental group

Description:

Patients will not receive any block

Treatment:

Drug: general anaesthetic technique only

Direct pecs block group

Experimental group

Description:

Pec I block will be given with 10 ml bupivacaine 0.25% which injected between two pectoral muscles and pecs II block will be given with 20 ml bupivacaine 0.25%.which given between pectoralis minor muscle and serratus muscle. Patients will receive direct pecs block by surgeon after closure of pectoralis muscle under direct vision and before skin closure.

Treatment:

Procedure: Direct pecs block

Ultrasound guided pecs

Experimental group

Description:

Pec I block will be given with 10 ml bupivacaine 0.25% which injected between two pectoral muscles and pecs II block will be given with 20 ml bupivacaine 0.25%.which given between pectoralis minor muscle and serratus muscle. Patients will receive ultrasound guided pecs block done after induction and before skin incision.

Treatment:

Procedure: Ultrasound guided pecs block