Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients

National Cancer Centre, Singapore

Status: Enrolling

Conditions: Nasopharyngeal Cancer; Other Cancer; Prostate Cancer

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT04340024

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Details and patient eligibility

About

Patients with cancers that are sensitive to radiotherapy treatment and/or patients who have experienced severe acute/ late side effects to radiotherapy will be recruited to the study. Blood and/or matched tumour-normal tissue pairs will be collected. Blood and/or tissue samples will be processed and studied for genetic and biochemical markers that have potential to be used for predicting sensitivity to radiation.

Enrollment: 5,000 estimated patients

Sex: All

Ages: 21 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with severe side effects from radiotherapy
• Patients with a type of cancer that is associated with sensitivity to radiotherapy

Exclusion criteria

• Age of patient must be between 21 (inclusive) and 99 (exclusive)