Discovery of Microbiome-based Biomarkers for Patients With Cancer Using Metagenomic Approach (ONCOBIOTICS)

Gustave Roussy

Status: Enrolling

Conditions: Cancer

Treatments: Other: Blood sample; Other: Stool

Study type: Observational

Funder types: Other

Identifiers

NCT04567446

2017-A02010-53

2017/2619 (Other Identifier)

Details and patient eligibility

About

Multicentric prospective study with collection of biological samples as part of type II research

Enrollment: 1,100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with cancer who will start treatment anticancer (see cohorts).
• Patient information and signature of the consent form before any specific procedure for the study. The patient must be able and must be inclined to cooperate in the study procedures.
• Patient affiliated to a social security scheme or beneficiary of a similar scheme.

Exclusion criteria

• Pregnant or lactating woman
• Patient under guardianship or curatorship or deprived of liberty by a decision judicial or administrative or patient unable to give his consent.

Trial design

1,100 participants in 3 patient groups

Patients with bladder cancer who will start cancer treatment

Description:

Collection of biological samples (stool and blood) and data from patients included in the study will be performed: 1. By identifying the patients who will start treatment anticancer (chemotherapy, hormone therapy, immunotherapy). 2. Collection of biological resources (all samples will be collected in fresh): stool and blood 3. Collection of clinical data corresponding to each patient included in the study by a clinical research assistant

Treatment:

Other: Stool

Other: Blood sample

Patients with Non-Small-Cell Lung cancer who will start cancer treatment

Description:

Collection of biological samples (stool and blood) and data from patients included in the study will be performed: 1. By identifying the patients who will start treatment anticancer (chemotherapy, hormone therapy, immunotherapy). 2. Collection of biological resources (all samples will be collected in fresh): stool and blood 3. Collection of clinical data corresponding to each patient included in the study by a clinical research assistant

Treatment:

Other: Stool

Other: Blood sample

Patients with kidney cancer who will start cancer treatment

Description:

Collection of biological samples (stool and blood) and data from patients included in the study will be performed: 1. By identifying the patients who will start treatment anticancer (chemotherapy, hormone therapy, immunotherapy). 2. Collection of biological resources (all samples will be collected in fresh): stool and blood 3. Collection of clinical data corresponding to each patient included in the study by a clinical research assistant

Treatment:

Other: Stool

Other: Blood sample