Disinfection Effect of Gaseous Ozone

Ankara University

Status: Completed

Conditions: Endodontic Treatment

Treatments: Procedure: 0.9% sterile saline solution combined with 80 seconds: The OzonyTronX® interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.; Procedure: 2.5% NaOCl with 80 seconds OzonyTronX®:The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.; Procedure: 2.5% NaOCl group: The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.

Study type: Interventional

Funder types: Other

Identifiers

NCT06470126

3/6

Details and patient eligibility

About

The current study aimed to investigate the effect of gaseous ozone in disinfection the root canals of primary teeth. Thirty-six primary molars of 36 completely healthy patients (aged 5-10) were included in the study.The included teeth were randomly divided into three groups as follows:

• sodium hypochlorite applied group, ozone applied group, ozone and sodium hypochlorite applied group.The study hypothesized that the antimicrobial efficiency of gaseous ozone would be higher than the other groups compared.

Full description

The current clinical randomized study's primary purpose was to investigate the antimicrobial efficiency of gaseous ozone on primary teeth root canals.The included teeth were randomly divided into three groups, and in each group, the root canal therapies of 12 primary teeth were done. In the first group, 2.5% sodium hypochlorite was applied as an irrigation agent. In second group, 0.9% sterile saline solution was combined with 80 seconds.

OzonyTronX® application. 2.5% sodium hypochlorite was applied as an intracanal medicament in combination with 80 seconds OzonyTronX® in the last group. Microbial analyses assessed the colonization of Candida albicans and Enterococcus faecalis before and after the procedure.

Enrollment: 36 patients

Sex: All

Ages: 5 to 10 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pediatric patients with no use of an antimicrobial agent in the last 3 months
• Teeth with positive responses to percussion and palpation, no sinus tract and intra-oral, extra-oral swelling,
• Teeth with no pathological and physiological mobility, and restorable with stainless steel crown.
• In radiographical examinations, the selected teeth needed to show the Res(i) and Res (1/4) scores according to the root resorption scoring system
• No radiolucency in the peri-radicular tissue and no internal-external root resorption were also among the including criteria. However, the teeth with lesions only in 1/3 percent of the bifurcation area were also included in the study

Exclusion criteria

• Patients who are not compatible with including criteria,
• Who cannot adopt the dental treatments,
• with whom rubber-dam İsolation was not possible were excluded from the study

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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36 participants in 3 patient groups

2.5% NaOCl

Active Comparator group

Description:

2.5% NaOCl was applied as a root canal irrigation agent.

Treatment:

Procedure: 2.5% NaOCl group: The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.

0.9% sterile saline solution combined with 80 seconds OzonyTronX®

Experimental group

Description:

0.9% sterile saline solution was combined with 80 seconds OzonyTronX® application as a root canal irrigation procedure.

Treatment:

Procedure: 0.9% sterile saline solution combined with 80 seconds: The OzonyTronX® interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.

2.5% NaOCl with 80 seconds OzonyTronX®

Experimental group

Description:

2.5% NaOCl was applied as an intracanal medicament in combination with 80 seconds OzonyTronX®

Treatment:

Procedure: 2.5% NaOCl with 80 seconds OzonyTronX®:The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.