Disorders of Systemic Glucose Balance

National Center for Research Resources (NCRR)

Status: Completed

Conditions: Hypoglycemia

Treatments: Procedure: Controlled hypoglycemia using insulin; Procedure: formula meal

Study type: Interventional

Funder types: NIH

Identifiers

NCT00006508

M01RR000036 (U.S. NIH Grant/Contract)

NCRR-M01RR00036-0770

Details and patient eligibility

About

We wish to identify people with hypoglycemia (low blood sugar) and ultimately determine why the blood sugar levels are so low. To do so, we will contrast the responses of patients suspected to have hypoglycemia with those of healthy subjects during standardized tests. Those tests may include: 1) a controlled hypoglycemia produced by administration of insulin, a blood sugar-lowering hormone, and sugar, 2) a formula meal, and 3) a period of up to 72 hours without food.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Patients with suspected hypoglycemia
• Healthy subjects (controls)
• Absence of known macrovascular disease or of known CNS disease by medical history, physical examination or ECG (exclusions for induced hypoglycemia)
• Ability to give informed consent