Disparities in Myocardial Infarction Remodeling According to Gender (REMOVE 2)

University Hospital, Angers

Status: Enrolling

Conditions: Ventricular Remodeling; Myocardial Infarction

Treatments: Diagnostic Test: cardiac imaging to assess left ventricular volumes and function

Study type: Interventional

Funder types: Other

Identifiers

NCT06343844

49RC23_0070

Details and patient eligibility

About

Following myocardial infarction, female individuals demonstrate a poorer prognosis, characterized by elevated rates of mortality and heart failure. A primary hypothesis suggests unfavorable cardiac remodeling in women. This remodeling, defined as alterations in cardiac size and shape post-infarction, necessitates repeated non-invasive imaging for study.

Enrollment: 1,650 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years
• First myocardial infarction with ST-segment elevation during the hospital phase
• Coronary angiography performed within 72 hours of the infarction
• Inclusion in the RIMA registry
• Patient affiliated or beneficiary of a social security scheme; Signature of informed consent

Exclusion criteria

• Patients already enrolled in the study
• Poor understanding of the French language
• Pregnant, breastfeeding, or postpartum women
• Individuals deprived of liberty by judicial or administrative decision; Individuals receiving psychiatric care under coercion
• Individuals subject to a legal protection measure; Individuals incapable of giving consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

1,650 participants in 1 patient group

case control registry

Other group

Description:

left ventricular remodeling measurement with cardiac echography

Treatment:

Diagnostic Test: cardiac imaging to assess left ventricular volumes and function