Distal Nerve Electrical Stimulation for Neuromuscular Reinnervation

National Cheng-Kung University

Status

Invitation-only

Conditions

Electrical Stimulation

Peripheral Nerve Regeneration

Treatments

Other: no nerve electrical stimulation

Other: Brief electrical stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT06687460

A-BR-112-085

Details and patient eligibility

About

During the process of nerve microsurgical reconstruction, 30 minutes of electrical stimulation is applied to the distal end of the damaged nerve to assess its potential benefits for nerve regeneration, functional recovery, slowing down the degeneration at the neuromuscular junction, and preventing muscle atrophy.

Enrollment

21 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Adults aged 18 and older
Acute peripheral nerve rupture between the elbow and wrist
Acute rupture of the median or ulnar nerve
Patients who have signed a valid written consent for surgery and trials

Exclusion criteria

History of injury or other causes leading to muscle and joint dysfunction in the affected area
Patients with radial nerve damage
Diabetes
History of arrhythmia
Stroke
Multiple sclerosis
Hereditary peripheral neuropathy
Amyotrophic lateral sclerosis (ALS)
Patients with a pacemaker
Presence of local infection at the wound site
Pregnant or breastfeeding women
Patients deemed unsuitable for enrollment by a physician