Distal Radial Artery Approach to Prevent Radial Artery Occlusion (DAPRAO)

National Institute of Cardiology Ignacio Chavez

Status: Completed

Conditions: Radial Artery Occlusion

Treatments: Procedure: Distal radial artery approach

Study type: Interventional

Funder types: Other

Identifiers

NCT04238026

INCAR-DG-DI-386-2019

Details and patient eligibility

About

The main complication of transradial intervention is radial artery occlusion (RAO). This is relevant because it limits the radial approach for future interventions and disables this conduit for coronary bypass grafts and arteriovenous fistula. Observational studies suggest that distal radial access could reduce RAO incidence.

The primary endpoint of our study is to compare the efficacy of the distal and proximal transradial approaches in terms of RAO incidence. The safety endpoint is the incidence of complications between these two methods.

Enrollment: 282 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Perceptible radial artery pulse
• Diagnostic or interventional procedure feasible to be performed with radial access.

Exclusion criteria

• Myocardial infarction with ST segment elevation in time for primary angioplasty.
• Cardiogenic shock or hemodynamic instability.
• Clinical, plethysmography or ultrasound suggestive of occlusion of the radial artery
• Prior recent radial artery access (1 month)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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282 participants in 2 patient groups

Distal radial artery approach

Experimental group

Description:

Puncture in the snuff box area of the arm with through and through technique, advancement of a wire and placement of an hydrophilic sheath introducer.

Treatment:

Procedure: Distal radial artery approach

Proximal radial artery approach

Active Comparator group

Description:

Puncture in the ventral side of the arm (2 cm proximal to the styloid apophysis) with through and through technique, advancement of a wire and placement of an hydrophilic sheath introducer.

Treatment:

Procedure: Distal radial artery approach