Distant Metastases and Long-Term Survival After Complete Resection of Neuroendocrine Tumors of the Appendix (SurvivApp)

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Neuroendocrine Tumors of the Appendix

Treatments: Other: Histopathological review

Study type: Observational

Funder types: Other

Identifiers

NCT03852693

SurvivApp

Details and patient eligibility

About

The aim of the present project is to evaluate the frequency of distant metastases and clinically relevant relapse and mortality, respectively, of aNEN (Neuroendocrine Neoplasms of the Appendix) measuring 1 - 2 cm.

The investigators hypothesize that the mortality rate of aNET (Neuroendocrine Tumors of the Appendix) measuring 1 - 2cm is less than 1%. Furthermore, the investigators hypothesize that regional lymph node metastases of aNET measuring 1 - 2 cm are clinically not relevant and are not associated with reduced survival. The investigators therefore hypothesize that oncological right-sided hemicolectomy has no impact on long-term survival after complete resection of aNET measuring 1 - 2 cm and that the malignant potential quo ad vitam of these tumors is lower than the risk of oncological hemicolectomy.

Enrollment: 278 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• The investigators will include all patients with aNET measuring 1 - 2 cm and complete resection between 01.01.2005 and 31.12.2010 of the primary tumor.

Exclusion criteria

Trial design

278 participants in 2 patient groups

Retrospective Group

Treatment:

Other: Histopathological review

Prospective Group

Treatment:

Other: Histopathological review