Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection

Schillerhoehe Hospital

Status and phase: Terminated; Phase 2

Conditions: Breast Cancer; Lung Cancer; Ovarian Cancer

Treatments: Other: exhalation analysis of breath sample

Study type: Interventional

Funder types: Other

Identifiers

NCT01383408

KSH-TCH-IIT-2011-1

Details and patient eligibility

About

Previous studies have shown that specially trained sniffer dogs are capable to discriminate breath samples of patients with lung cancer and healthy individuals. So far it is not known whether this differentiation is specific for lung cancer or just identifies any form of (solid) tumor. Therefore, the dog's ability to differentiate between lung cancer, breast cancer and ovarian cancer is tested.

Enrollment: 752 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• histologically confirmed lung or breast or ovarian cancer

Exclusion criteria

• other cancers
• previous medical intervention within the last 14 days before gathering of the breath sample

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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752 participants in 4 patient groups

healthy individual

Sham Comparator group

Description:

healthy individual with no lung disease and no history of cancer including lung cancer

Treatment:

Other: exhalation analysis of breath sample

lung cancer

Experimental group

Description:

patients with histologically confirmed lung cancer, but no history of other cancer

Treatment:

Other: exhalation analysis of breath sample

breast cancer

Experimental group

Description:

patients with histologically confirmed breast cancer, but no history of other cancer

Treatment:

Other: exhalation analysis of breath sample

ovarian cancer

Experimental group

Description:

patients with histologically confirmed ovarian cancer, but no history of other cancer

Treatment:

Other: exhalation analysis of breath sample