Distinction of Cone Outer Segment Tips by Spectral-Domain Optical Coherence Tomography in Normal Eyes

Kyorin University

Status: Completed

Conditions: Healthy

Treatments: Other: Optical coherence tomography

Study type: Observational

Funder types: Other

Identifiers

NCT01316003

KyorinEye004

Details and patient eligibility

About

The aim of this study is to investigate the incidence and possible causes of obscured or disrupted cone outer segment tips line at fovea in spectral-domain optical coherence tomography images of normal eyes.

Full description

Thirty-seven eyes of 37 individuals without eye diseases were included in this study. Optical Coherence Tomography (OCT) images were taken using Cirrus HD-OCT (Carl Zeiss Meditec) with 5 line raster and high-definition 5 line raster modes. Images with signal strength weaker than 5/10 were excluded. Distinction of COST line and the integrity of COST line, external limiting membrane, and the photoreceptor inner segment and outer segment junction at the fovea were recorded. Demographic data, refractive error of the eyes, signal strengths of the OCT images were acquired for analysis.

Enrollment: 37 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• individuals without eye diseases

Exclusion criteria

• individuals with eye diseases

Trial design

37 participants in 1 patient group

Normal subjects

Description:

Thirty-seven eyes of 37 individuals without eye diseases

Treatment:

Other: Optical coherence tomography