Distribution of Pulmonary Ventilation in Lateral Decubitus of Healthy Adults Under Non-Invasive Mechanical Ventilation

Attikon University Hospital

Status: Completed

Conditions: Noninvasive Ventilation; Patient Positioning

Treatments: Device: Positive End Expiratory Pressure 10 H2O; Device: Positive End Expiratory Pressure 5 H2O

Study type: Interventional

Funder types: Other

Identifiers

NCT06489509

EBD2878

Details and patient eligibility

About

The aim was to investigate via impedance tomography apparatus the distribution of pulmonary ventilation at a lateral position at different Continuous Positive Airway Pressure levels (0, 5, 10 cm Η2Ο) in healthy subjects.

Full description

In lateral decubitus, the largest percentage of pulmonary ventilation of non-sedated subjects is distributed mainly in the dependent lung. The aim It was to investigate via impedance tomography apparatus the distribution of pulmonary ventilation at a lateral position at different Continuous Positive Airway Pressure levels (0, 5, 10 cm Η2Ο) in healthy subjects. The volunteers were noninvasively ventilated in both lateral positions and supine positions at the beginning and end of the process. It is concluded that implementing Non-Invasive Ventilation in the lateral body position resulted in increased ventilation of the dependent lung. In contrast, the respective ventilation of the non-dependent lung was further decreased.

Enrollment: 10 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy Volunteers

Exclusion criteria

• Chronic respiratory disease
• BMI>40
• Smoking history

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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10 participants in 3 patient groups

Supine position

Active Comparator group

Description:

Supine experimental position

Treatment:

Device: Positive End Expiratory Pressure 5 H2O

Device: Positive End Expiratory Pressure 10 H2O

Right position

Active Comparator group

Description:

Right lateral decubitus

Treatment:

Device: Positive End Expiratory Pressure 5 H2O

Device: Positive End Expiratory Pressure 10 H2O

Left position

Active Comparator group

Description:

Left lateral decubitus

Treatment:

Device: Positive End Expiratory Pressure 5 H2O

Device: Positive End Expiratory Pressure 10 H2O