Diurnal Variation in Rectal Diameter

Line Modin

Status

Completed

Conditions

Constipation

Treatments

Procedure: Transabdominal ultrasound

Study type

Observational

Funder types

Other

Identifiers

NCT01695915

DV-Rect-UL

Details and patient eligibility

About

The purpose of the study is to determine the diurnal variation of rectal diameter in healthy and constipated children using transabdominal ultrasound.

Enrollment

30 patients

Sex

All

Ages

4 to 12 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Constipated Inclusion Criteria:

Children from 4 to 12 years with previously diagnosed simple constipation defined by ROME III criteria, which at inclusion is in maintenance therapy with PEG + E and has been in treatment for at least 1 month.

Exclusion Criteria:

Children with known organic causes of constipation, including Hirschsprungs disease, spinal and anal congenital abnormalities, previous surgery on the colon, inflammatory bowel disease, allergy and metabolic or endocrine diseases.
Children receiving drugs known to affect bowel function during a 2 month period before initiation besides laxatives.

Healthy inclusion Criteria:

Children between 4 and 12 years of age.

Healthy exclusion Criteria:

Children with known organic causes of constipation, including Hirschsprungs disease, spinal and anal congenital abnormalities, previous surgery on the colon, inflammatory bowel disease, allergy and metabolic or endocrine diseases.
Children receiving drugs known to affect bowel function during a 2 month period before initiation.
Children with a previous history of constipation, fecal incontinence and / or urinary tract infections.